Case Report of Four Different Primary Mesenteric Neoplasms and Review of Literature

Our plain-English summary of Case Report of Four Different Primary Mesenteric Neoplasms and Review of Literature, by Y. Yagmur, S. Akbulut, S. Gumus, et al (Iranian Red Crescent Medical Journal, 2016).

The study

• Authors: Y. Yagmur, S. Akbulut, S. Gumus, M. Babur, M.A. Can
• Journal: Iranian Red Crescent Medical Journal
• Published: 2016;18(10):e28920
• Type of article: Case report
• Cited by: 6 articles, as counted by NIH iCite
• Read it: PubMed · Publisher · Free full text

Abstract

Introduction: It is rare for primary tumors to arise from the mesentery. Lymphangiomas appear as congenital malformations of the lymphatic system or benign neoplasms as a large, thin-walled, often multilocular cyst. Mesenteric infiltration is common and during surgical treatment, adjustment of structures such as the bowel and resection of the spleen may be required. Cystic mesotheliomas are rare, benign tumors that originate from the peritoneal mesothelium and are more common in women. Mesenteric cysts are mostly benign and rare intra-abdominal tumors, and can be seen as occupying a large cyst. Malignant fibrous histiocytoma is a rare pleomorphic sarcoma that is more commonly encountered in men. After the extremities, the second most common areas to be affected are the retroperitoneum and peritoneal cavity.

Case Presentation: We encountered four cases of different primary mesenteric neoplasms that were operated at the Gazi Yasargil teaching and research hospital, department of general surgery, Diyarbakir, Turkey, between 2013 and 2014. We reviewed these primary mesenteric neoplasms and compared them with previous literature.

Conclusions: Primary mesenteric tumors are rare and mostly benign tumors. Complete surgical excision is necessary for all tumors and follow-up is necessary after surgery for malignant fibrous histiocytoma due to recurrence.

In plain English

This article was a case report of four patients operated on for different rare tumors arising in the mesentery (tissue holding the intestines in place) at Gazi Yasargil Teaching and Research Hospital in Diyarbakir, Turkey, between January 2013 and May 2014. The authors compared the cases with earlier reports. A 45-year-old woman had a lymphangioma. A 61-year-old woman had a benign cystic mesothelioma. Both tumors were removed laparoscopically, and neither patient showed signs of the tumor at one year. A woman listed as 20 years old had a mesenteric (omental) cyst about 33 by 14 cm, removed along with her spleen; she was well at 11 months. A 52-year-old man (per the table) had a malignant fibrous histiocytoma, a type of sarcoma. It recurred by the 12-month visit and was removed again, and the patient was well 4 months later. The article did not report asbestos exposure for any patient. The authors concluded that follow-up is needed for all these tumors because of recurrence, especially for malignant fibrous histiocytoma.

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report (case series of four patients) with a review of earlier literature
• Who was studied: Four patients with different primary mesenteric tumors operated on at Gazi Yasargil Teaching and Research Hospital, Department of General Surgery, Diyarbakir, Turkey, between January 2013 and May 2014. By the table: a 45-year-old woman, a 61-year-old woman, a 20-year-old woman and a 52-year-old man.
• Main results:
  • Case 1, a 45-year-old woman: subhepatic cystic masses were removed laparoscopically and pathology was consistent with lymphangioma. At one year she was well, with no signs of a cystic mass on ultrasonography.
  • Case 2, a 61-year-old woman: a multicystic mass below the liver and small cysts around the cecum were removed laparoscopically. Pathology showed multilocular peritoneal inclusion cysts consistent with benign cystic mesothelioma. At one year ultrasonography showed no sign of cystic mesothelioma.
  • Case 3, listed in the table as a 20-year-old woman: a 33 × 14 × 7.5 cm cystic mass consistent with mesenteric (omental) cysts was removed together with the spleen. She was well at 11 months.
  • Case 4, listed in the table as a 52-year-old man: a 22 × 18 × 18 cm mass was completely excised and pathology was consistent with malignant fibrous histiocytoma (MFH).
  • Case 4: the MFH recurred by the 12-month follow-up, with three mesenteric masses on CT. These were surgically removed, and pathology again showed malignant fibrous histiocytoma. The patient received no adjuvant chemotherapy or radiation and was well at the 4-month visit after the second operation.
• The authors' conclusion: The authors concluded that primary mesenteric tumors are very rare. Lymphangiomas and cystic mesotheliomas are benign, and omental and mesenteric cysts are mostly benign, while MFH is a highly malignant sarcoma. Ultrasonography and CT follow-up is necessary in all primary mesenteric neoplasms because of recurrence, which is high especially for MFH.

Topics

Medical terms in this study, explained in our Lexicon: Neoplasm, Mesentery, Mesothelioma, Mesothelium, Pleomorphic, Sarcoma, Retroperitoneum, Peritoneal Cavity.

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